My option would be to leave from Newlyn,as you do not have the tidal gate constraints, If possible take the inshore passage around Landsend and work up to Padstow, If weather is good continue up to Ilffracome. From here on you will need to work the tides. Leave the outer anchorage about one hour before low water working close up inshore then pick up the early flood.
Options..from here..Barry to see out the tide then leave at low water and take the full flood all the way up to Avonmouth and Bristol
If you can make Portishead from Combe OK. But you will need a fair tide for Avonmouth.
Mooring at Barry Ok. No charge Lay along side a boat in the row after the lifeboat East side of my boat Dawn Star