I usually do this trip a min of twice a year and sometimes 4. But never in one go - mind you we're never 3 up. Usually just 2 in a 39 footer or my 34 footer, and with just 2 its too much like hard work.

By inclination I stop in Penzance. I like the place and Newlyn is full of big steel hulled fishing boats which makes me nervous. You can leave Penzance as the lock is about to close and either waste an hour hanging off one of their outer buoys or just sail slowly and you will catch the first of the flood on the inner passage. Incidentally the inner passage is not one to be done for the first time in the dark or in bad weahter, but its so much better than the route outside the longships light that its worth waiting a tide for.

In good conditions its not too difficult to time things so you can round both cape cornwall and the lizard in one leg, missing out Penzance and / or Newlyn altogether. If so, your next good port of call is Padstow. Going into the harbour means locking in but you can anchor subject to conditions just by Stepper point. Tide up the north cornish coast isnt too much so you need to time things so that you have the flood with you when you get to Hartland point ie you leave Padstow when the tide is still ebbing.

Up to you whether you anchor off Lundy (good in S and W but avoiid if there is E in the wind) or in the outer harbour at Ilfracombe. Either way, from these places you go with the tide unless you like really long passages. You likely wont make it from Combe to Bristol in time to go up the Avon - 60 nm (more from Lundy) and maybe 6 hours to do it in even allowing for later tides up the channel. So plan on sitting out a tide at somewhere like Barry.

So my suggested route would be either Falmouth>Padtow>Ilfracombe>Barry or Falmouth>Penzance>Ilfracombe>Barry. If you're feeling really macho then Falmouth>Ilfracombe/Lundy>Barry

But dont kid yourself that Lundy to Bristol direct will be anything other than a very long slog with lots of time spent making little or no progress against a foul tide.