I strongly suggest you use the Roxio forum. Here's a start http://forums.support.roxio.com/index.php?showtopic=805

Assuming it's V4 then there is a lot to check for. A few example problems you encounter might be that you suddenly lose access to a USB port or your machine no longer recognises a drive that you know is there; if you try and load another/similar application then CD Creator may affect that as well.

Here is a typical problem left by V4 http://forums.support.roxio.com/index.php?showtopic=16446