We were in Samos marina last year on a charter. We have friends that live there and I'm flying out there in a couple of weeks. Samos is a lovely island and is relatively undeveloped tourist-wise, but is suffering, like all of Greece, from the effects of the government's austerity programme. The marina is modern, well run and the staff are friendly and helpful. There is a chandlery and a couple of bars/restaurants on site, and it’s a 20 min walk into Pythagorion, with lots of bars, restaurants, car hire and a small supermarket just out of town near the airport. We would certainly consider it as a Greek base. The outlying islands are lovely and of course you can almost chuck a biscuit onto a Turkish beach from there. The main downside is that as far as I know there are no direct flights from the UK in the winter and going via Athens is expensive and takes forever. Charter flights seem plentiful and reasonably cheap in the summer though.